Our first collaborative review article, written with Prof. Jennifer Munson and Jenn Hammel of Virginia Tech teamed up with Pompano Lab students Sophie Cook and Maura Belanger, is out in Annual Reviews of Biomedical Engineering!
We cover models of immune organs (lymph node, bone marrow, spleen, lymphatics, etc) and models of peripheral organs that feature immunity.
For each organ, we systematically review models based on
(i) tissue slices
(ii) microfluidics and organs-on-chip
(iii) engineered models, e.g. 3D cultures
The focus is primarily on models of healthy tissue, though with some discussion of models of inflammatory disease as well. Enjoy!
JH Hammel’, SR Cook’, MC Belanger’, JM Munson, and RR Pompano. “Modeling Immunity In Vitro: Slices, Chips, and Engineered Tissues.” Annual Review of Biomedical Eng, 2021, online ahead of print. [pubmed] ‘Equal contributions.
