Publications: Organs-on-Chip for Immunology
For reprints of any of these publications, please email Dr. Pompano: rpompano [at] virginia.edu. Any PDFs are provided solely for personal or educational use. We are fortunate to have several stellar undergraduate researchers in the lab. (#) Indicates undergraduate co-author.
Rebecca R. Pompano. "Boosting B cells in blood-derived organoids." Nature Materials (2025). https://doi.org/10.1038/s41563-024-02113-6
Jonathan M Zatorski*, Djuro Raskovic*, Abhinav Arneja, Saweetha Kiridena, Tochukwu Ozulumba, Jennifer H Hammel, Parastoo Anbaei, Jennifer E Ortiz-Cárdenas, Thomas J Braciale, Jennifer Munson, Chance John Luckey, Rebecca R Pompano. “Initiation of primary T cell—B cell interactions and extrafollicular antibody responses in an organized microphysiological model of the human lymph node.” bioRxiv 2025.01.12.632545 [Preprint available, prior to peer review]
*Equal contributions
Jennifer H Hammel, Abhinav Arneja, Jessica Cunningham, Maosen Wang, Sophia Schumaecker, Yamilet Macias Orihuela, Tochukwu Ozulumba, Jonathan Zatorski, Thomas J Braciale, Chance John Luckey, Rebecca R Pompano, Jennifer M Munson, “Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress.” bioRxiv 2024.12.03.622729. [Preprint available, prior to peer review]
Sophie R. Cook, Alexander G. Ball, Anwaruddin Mohammad, Rebecca R. Pompano. “A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node.” Lab on a Chip, 2025, in press. DOI: 10.1039/D4LC00489B [Open access at publisher]
Tochukwu Ozulumba, Jonathan M. Zatorski, Abhinav Arneja, Jennifer H. Hammel, Thomas J. Braciale, Chance John Luckey, Jennifer M. Munson, Rebecca R. Pompano. “Mitigating reactive oxygen species production and increasing gel porosity improves lymphocyte viability and fibroblast spreading in photocrosslinked gelatin-thiol hydrogels.” In revision. [BioRxiv preprint available, prior to peer review]
Hannah B. Musgrove, Sophie R. Cook, and Rebecca R. Pompano. “Parylene-C coating protects resin 3D printed devices from materials erosion and cytotoxicity.” ACS Applied Bio Materials, 2023, 6, 8, 3079–3083 [Publisher link] [ChemRxiv][Design Files]
Ozulumba T, Montalbine AN (#), Ortiz-Cárdenas JE, Pompano RR. “New tools for immunologists: Experimental and computational models of lymph node function from cell to tissue levels”. Frontiers in Immunology, 2023, 14, doi: 10.3389/fimmu.2023.1183286. Review article, open access.
Ortiz-Cárdenas JE, Zatorski JM, Arneja A, Montalbine AN (#), Munson JM, Luckey CJ, & Pompano RR. “Towards spatially-organized organs-on-chip: Photopatterning cell-laden thiol-ene and methacryloyl hydrogels in a microfluidic device.” Organs-on-a-Chip, 2022, 4, 100018 [Publisher link]
Featured in Emerging Investigators in Organs-on-a-Chip special issue.
Jennifer H. Hammel, Jonathan M. Zatorski, Sophie R. Cook, Rebecca R. Pompano, Jennifer M. Munson. “Engineering in vitro immune-competent tissue models for testing and evaluation of therapeutics,” Advanced Drug Delivery Reviews (2022). 182, 114111. [Publisher link]
Megan A. Catterton, Alexander G. Ball, and Rebecca R. Pompano. "Rapid Fabrication by Digital Light Processing 3D Printing of a SlipChip with Movable Ports For Local Delivery to Ex Vivo Organ Cultures" Micromachines (2021) 12, no. 8: 993. https://doi.org/10.3390/mi12080993 [Link, open access]